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420 news : Against The Wall with JJink

Number of Marijuana Users Grows in the United States

October 4, 2016 by  
Filed under 420 news, General News

Evelyn Robinson /Against the Wall 60567160824797010213532

As of June, 2016, some 25 states and Washington D.C. have officially legalized the use of marijuana for medical purposes, with a further three states awaiting the results of ballot measures or pending law changes. Although medical marijuana laws are now the norm, their nature varies greatly from state to state, which has important implications as far as the health and welfare of citizens are concerned – especially those battling illnesses whose symptoms are eased by marijuana, including epilepsy and illness producing chronic pain. In some states, people are allowed to cultivate marijuana for medical use (limits on the number of permitted plants vary from state to state); among these states, some only permit people to grow marijuana if they do not have a state dispensary or for financial reasons. In other states, the term ‘medical marijuana’ simply refers to marijuana extract (not the plant or leaves).
Amidst these subtle differences with big implications, meanwhile, the use of marijuana for recreational in the United States has steadily increased over the past few years, owing in no small part to the decreased perception of the drug being harmful. A large-scale survey of over half a million adults, undertaken between 2002 and 2014 and published last month in The Lancet, has found that marijuana use continues to increase and that the drug has become increasingly more potent in the last decade. The authors of the study note that these new developments mean that improved education and prevention messages regarding the nature of and risk factors involved in using marijuana, must be aimed for.
The authors also noted that increased use of marijuana did not lead to greater abuse or dependence among adults in America. Thus far, the impact of state law changes need to be assessed, and continued monitoring of use and possible disorders, would be required.
The study showed that from 2002 to 2014, marijuana use increased from 10.4 per cent to 13.3 per cent; so, too, did the percentage of adults who first began using marijuana in the previous year, rise significantly (from 0.7 per cent to 1.1 per cent within the same time frame). More people are also using the drug on a daily basis – the percentage of those who take marijuana five days a week on average has risen from 1.9 per cent to 3.5 per cent. People also do not perceive that smoking marijuana is risky (33.3 per cent deemed the practice potentially harmful in 2014, compared to 50.4 per cent in 2002). The authors claim that changes in the perception of marijuana’s safety, began to change in 2007. The paradigm shift can partly be attributed to the legalization of medical marijuana in many states, and to its legalization for non-medical purposes, in several jurisdictions.
The fact that increased use has not led to greater abuse/addiction, reflects that possibility that those who have started using marijuana, or doing so less frequently. Those who have been found to be at a greater risk for addiction include males, the youth, those with lower levels of education, those who do not work full-time, persons with depression and those who consume tobacco or other substances.  Among adolescents, risk factors for the consumption of drugs include having a low grade point average, early alcohol used, low self-confidence, psychopathology, and having a poor relationship with their parents. Those whose personality tended to be sensation seeking, also had a higher likelihood of dabbling in marijuana and other drugs.
The authors stated, however, that the full effects of legalization needed to be studied over time, via large-scale surveys such as the National Survey on Drug Use and Health, and Monitoring the Future (which focuses on drug use among the youth). Comparisons should be made between sample populations in states that have legalized marijuana for both recreation and medical use, and those which have not.
The authors also noted that their survey, although large and extended in time, did not take into account specific members of the population (including the homeless, those who had been imprisoned, and those living in shelters). Therefore, the actual rate of those who use and abuse the drug, could actually be much higher. The study also failed to look into the link between serious psychiatric disorders such as schizophrenia, and the likelihood of marijuana use.
60567160824797010213532

Dennis Hill- a Bio chemist kills his Prostate cancer using cannabis oil talks about endo-canabinoids

October 31, 2015 by  
Filed under 420 news, Video


Dennis Hill, a biochemist from the cancer industry, kills his own advanced stage prostate cancer using marijuana. The concentrated cannabis oil, aka “rick simpson oil,” or marijuana extract, is the essential oils from the marijuana plant which is extracted and condensed to a tiny dose the size of a half of grain of rice

The Endocannabinoid System – How cannabis oil works

October 30, 2015 by  
Filed under 420 news, Video

Cannabis Science — The Endocannabinoid System: How cannabis oil works.
Since 1974 studies have shown that cannabis has anti-tumor effects. The results of the 1974 study, reported in an Aug. 18, 1974, Washington Post newspaper feature, were that cannabis’s component, THC, “slowed the growth of lung cancers, breast cancers and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent.” In 1975 an article in the Journal of the National cancer institute titled “Antineoplastic Activity of Cannabinoids,” they reported that “Lewis lung adenocarcinoma growth was retarded by the oral administration of tetrahydrocannabinol (THC) and cannabinol (CBD). Mice treated for 20 consecutive days with THC and CBD had reduced primary tumor size.”
In 1998, a research team at Madrid’s Complutense University Led by Dr. Manuel Guzman discovered that THC can selectively induce programmed cell death in brain tumor cells without negatively impacting surrounding healthy cells. They reported in the March 2002 issue of “Nature Medicine” they had destroyed incurable brain cancer tumors in rats by injecting them with THC. And in 2007 even Harvard Researchers found that compounds in cannabis cut the growth of lung cancer. There is also an organization called The SETH Group that showed compounds in cannabis can stop the growth of human glioblastoma multiforma (GBM) brain cancer cells. The SETH Group says “No chemotherapy can match this nontoxic anti-cancer action.” Even last year in 2012 a pair of scientists at California Pacific Medical Center in San Francisco found THC stops metastasis in many kinds of aggressive cancer.

Thanks http://www.youtube.com/user/alamJaw?f…

HOW and WHY does Cannabis Cure Cancer – Scientific Explanation

October 30, 2015 by  
Filed under 420 news, Video


Please Re-Upload and Share this Video with Everyone!
Health Professionals, Doctors and Scientists Interviewed
They are listed in order of appearance in this video…

Sign Global Petition to END THE WAR ON DRUGS
Sign Petition @ http://www.breakingthetaboo.info/

Listed in Order of Appearance:

Jeffrey Hergenrather M.D.
President of the Society of Cannabis Clinicians

http://thesethgroup.org/

Dr. Robert Melamed Ph.D.
Associate Professor and Biology Chairman in the Biology Department at the University of Colorado and of Cannabis Science

Dr. Manuel Guzman
Professor of Biochemistry – University of Madrid

Paul Armentano
Deputy Director NORML

Prakash Nagarkatti, Ph.D.
Vice President for Research University of South Carolina Columbia
Distinguished Professor

Dr. Donald Tashkin M.D.
Professor of Pulmonary Medicine, UCLA

Video of Cannabis Killing Cancer Cells
Link http://youtu.be/fzVZCSQf-fM

These videos clips are from the following documentaries:

Len Richmond’s ” What if Cannabis Cures Cancer ”

PBS Montana ” Clearing the Smoke – Science of Cannabis ”

Medical Cannabis and its Impact on Human Health

Sign Global Petition to END THE WAR ON DRUGS
Sign Petition @ http://www.breakingthetaboo.info/

Landon Riddle’s Story: 3 Year old beats Leukemia with cannabis oil (MORE at cureyourowncancer.org)

October 30, 2015 by  
Filed under 420 news, Video

He’s only 3 years old, but Landon Riddle is already the focus of a medical marijuana fight in Colorado.
Landon has acute lymphocytic leukemia, or ALL, a cancer of the blood and bone marrow. It’s the most common cancer in children.
His mother says his condition has improved so much following treatment with medical marijuana that chemotherapy isn’t needed. But the Children’s Hospital of Colorado, she says, disagreed.
It all started back in September 2012. Landon, then 2, was living with his mother, Sierra Riddle, in St. George, Utah, when he developed a sore throat and swollen lymph nodes. The emergency room doctor said it was a virus and sent him home.
School stops giving boy medical pot Is medical marijuana right for a 3-year-old? “Please don’t let my daughter die”
Two days later he went back. His armpits were swollen.
“They thought it was either a virus or infection in the lymph nodes, so they gave him some antibiotics,” Sierra Riddle says.
But on the fifth day, his mother says she was changing his diaper and noticed his groin was also swollen, as well as his abdomen and throat. He was having trouble breathing.
That time, she got a frightening diagnosis: cancer.
New York governor announces plan for medical marijuana at hospitals
Landon was flown to a children’s hospital in Salt Lake City.
“His whole chest was full of leukemia tumors, which is why he couldn’t breathe,” his mother says. “They started him on chemo, but told us that he probably wasn’t going to make it.”
Landon’s cancer had quickly progressed, leading doctors to give him an 8% chance of survival, she says.
In general, ALL is one of the most curable cancers. According to the American Cancer Society, more than 90% of children diagnosed with the disease survive.
Chemotherapy is the standard treatment, and Riddle says doctors put Landon on a four-year treatment plan. The first two months of chemo went fairly well, but then Landon became extremely ill.
“Most days he couldn’t get off the couch,” Riddle remembers. “He would just lay there and throw up and throw up.”
Riddle says he also developed neuropathy — a symptom of nerve damage that can cause weakness, numbness and pain — in his legs that left him barely able to walk.
Around that time, a friend set up a Facebook page called Offer Hope for Landon, and recommendations started streaming in, including several endorsing cannabis — medical marijuana — as a treatment.
Medical marijuana, however, isn’t legal in Utah. Still, desperate for answers, Sierra Riddle and her mother, Wendy Riddle, started looking into it.
They considered going to California or Oregon. Then their research led them to the Stanley brothers in Colorado. The six brothers are one of that state’s biggest cannabis growers and dispensary owners.
The Stanleys produce about 500 pounds of medical marijuana a year. At the time, much of it was high in THC — tetrahydrocannabinol, the psychoactive ingredient in pot that gets users high but also helps patients with an array of conditions including pain and nausea.
But the Stanleys were also growing something quite revolutionary: a plant cross-bred to reduce the THC and increase another compound found in cannabis called cannabidiol, or CBD. Many researchers believe CBD is one of the compounds in marijuana that has medicinal benefits. According to the National Cancer Institute, it’s thought to have significant analgesic, anti-inflammatory and anti-tumor activity without the psychoactive effect.
The Stanleys expect to produce over 1,000 pounds this year, most of it the cross-bred variety, according to Joel Stanley.
Dr. Sanjay Gupta: Why I changed my mind on weed
Riddle, herself a recovering heroin addict, struggled with the idea of giving Landon marijuana.
“I was telling my mom, you know, ‘We really need to think about this.'”
But, says Riddle, her son was already prescribed medications like OxyContin and morphine — medications with significant side effects.
Landon suffered from stomach failure, and “the OxyContin made him so miserable, when he had hair, he would literally try to pull his hair out.”
In the end, she decided she had nothing else to lose and moved to Colorado. She rented a room, got Landon’s medical marijuana card and began giving him marijuana — THC for the pain and nausea, but also CBD. The dose was based on Landon’s weight. He first took it in oil form, but now takes a pill.
Once the doses started, “Landon’s (red and white blood cell) counts increased dramatically,” she says.
Six months later, encouraged by Landon’s progress, she stopped his chemotherapy treatments completely.
“Once I took the chemo out, I see these amazing results. And no more need for blood transfusion and platelet transfusions,” Riddle says. “I think that the chemo in combination with the cannabis did put him into remission and now the cannabis will keep him there.”

CANNABIS OIL CURED MY TERMINAL CANCER

October 30, 2015 by  
Filed under 420 news, Video

In an exclusive interview with MedicalMarijuana.co.uk, David Hibbitt explains how his use of cannabis oil helped him treat his terminal cancer

Molecular Biologist Explains How THC Completely Kills Cancer

October 24, 2015 by  
Filed under 420 news, Video


 

Below is a video of Dr. Christina Sanchez, a molecular biologist at Compultense University in Madrid, Spain, clearly explaining how THC (the main psychoactive constitute of the cannabis plant) completely kills cancer cells.

Not long ago, we published an article examining a case study recently published where doctors used cannabis to treat Leukemia, you can read more about that here. To read more articles and view studies about how cannabis is an effective treatment and cure for cancer, click here.

Cannabinoids refer to any of group of related compounds that include cannabinol and the active constituents of cannabis. They activate cannabinoid receptors in the body. The body itself produces  compounds called endocannabinoids and they play a role in many processes within the body that help to create a healthy environment. I think it’s also important to note that cannabis has been shown to treat cancer without any psychoactive effects.

Cannabinoids have been proven to reduce cancer cells as they have a great impact on the rebuilding of the immune system. Although not every strain of cannabis has the same effect, more and more patients are seeing success in cancer reduction in a short period of time by using cannabis. Contrary to popular  belief, smoking cannabis does not assist a great deal in treating disease within the body as therapeutic levels cannot be reached through smoking. Creating oil from the plant or eating the plant is the best way to go about getting the necessary ingredients, the cannabinoids.

The world has come a long way with regards to accepting this plant as a medicine rather than a harmful substance. It’s a plant that could benefit the planet in more ways than one. Cannabis is not something offered in the same regard as chemotherapy, but more people are becoming aware if it, which is why it’s so important to continue to spread information like this. Nobody can really deny the tremendous healing power of this plant.

New Ruling Finds Cannabis To Be The Most Medicinal Plant In The World

October 21, 2015 by  
Filed under 420 news, General News

source:hempfor future
More than a dozen U.S. states have now completely decriminalized the act of possessing marijuana and both Colorado and Washington have made it legal to possess, sell, transport and cultivate the plant. But soon it may be legalized across the entire country following a decision Thursday by the federal government.

In a historic and significant moment in American history, last November, Colorado became the first US state to legalize marijuana for recreational use. The impact of the decision could soon ripple across the entire country with vast opportunities to educate millions on the top health benefits of marijuana.
With the passage of I-502 in the 2012 Washington State election, marijuana also became legal in Washington–not just for medical use, but also for recreational use–and Alaska, California, Connecticut, Maine, Massachusetts, Nevada, New York, Nebraska, North Carolina, Ohio, Oregon, and Vermont have all decriminalized marijuana.
Consumption and sale of marijuana is still illegal in all other states, though some cities and towns have passed local laws decriminalizing it or making it a low priority for law enforcement officers.
There are also movements in many states to legalize pot, including legalization bills introduced in many other states.
For other states to mimic the systems in Colorado and Washington, they will first have to get legalization laws on their ballots or in their state houses, which could post a challenge, he said.
After Washington state and Colorado passed laws in November 2012 legalizing the consumption and sale of marijuana for adults over 18, lawmakers in both states waited to see whether the federal government would continue to prosecute pot crimes under federal statutes in their states.
Both Colorado and Washington have been working to set up regulatory systems in order to license and tax marijuana growers and retail sellers, but have been wary of whether federal prosecutors would come after them for doing so. They are the first states to legalize pot, and therefore to go through the process of trying to set up a regulatory system.
Ruling Signals The End is Near For Marijuana Prohibition
Last Thursday, the Department of Justice announced that it would not prosecute marijuana crimes that were legal under state law, a move that could signal the end of the country’s longtime prohibition on pot is nearing. “It certainly appears to be potentially the beginning of the end,” said Paul Armantano, deputy director of the pot lobby group NORML.
The memo sent to states Thursday by the DOJ said that as long as states set up comprehensive regulations governing marijuana, there would be no need for the federal government to step in, a decision that will save the Justice Department from having to use its limited resources on prosecuting individuals for growing or smoking marijuana.
“This memo appears to be sending the message to states regarding marijuana prohibition that is a recognition that a majority of the public and in some states majority of lawmakers no longer want to continue down the road of illegal cannabis, and would rather experiment with different regulatory schemes of license and retail sale of cannabis,” Armantano said.
In 2011 the federal government decreed that marijuana had no accepted medical use use and should remain classified as a highly dangerous drug like heroin. Accepting and promoting the powerful health benefits of marijuana would instantly cut huge profits geared towards cancer treatment and the U.S. would have to admit it imprisons the population for no cause. Nearly half of all drug arrests in the United States are for marijuana.
According to MarijuanaNews.com editor Richard Cowan, the answer is because it is a threat to cannabis prohibition “…there really is massive proof that the suppression of medical cannabis represents the greatest failure of the institutions of a free society, medicine, journalism, science, and our fundamental values,” Cowan notes.
While Colorado and Washington have not yet set up their regulatory systems, both states will likely sell licenses to farmers who want to grow marijuana as well as to manufacturing plants and retail sellers. The marijuana will also likely be taxed at each stage of its growth, processing, and sale.
“In both Colorado and Washington, legalization was done by citizens with no participation by elected representatives until they had to pass laws to comply with the initiative. In other initiative states I would expect such measures – I would expect a new one in California, for instance – and roughly half the states permit this and the rest don’t.
“In the states that do have initiatives I expect efforts to get it on the ballot. The other half it will be much tougher. It’s hard to get elected representatives to do this,” Collins said.
Armantano is more optimistic about the spread of legalized pot. He compared the DOJ’s announcement to the federal government’s actions toward the end of alcohol prohibition in America a century ago, when states decided to stop following the federal ban on alcohol sales and the federal government said it would not step in and prosecute crimes.
“For first time we now have clear message from fed government saying they will not stand in way of states that wish to implement alternative regulatory schemes in lieu of federal prohibition,” Armantano said.
He predicted that within the next one to three years, five or six other states may join Colorado and Washington in legalizing the drug, setting the stage for the rest of the country to follow.
The Age of Deception is Ending
In 2003, the U.S. Government as represented by the Department of Health and Human Services filed for, and was awarded a patent on cannabinoids. The reason? Because research into cannabinoids allowed pharmaceutical companies to acquire practical knowledge on one of the most powerful antioxidants and neuroprotectants known to the natural world.
The U.S. Patent 6630507 was specifically initiated when researchers found that cannabinoids had specific antioxidant properties making them useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention.
Besides the top 10 health benefits below, findings published in the journalPLoS ONE, researchers have now have now discovered that marijuana-like chemicals trigger receptors on human immune cells that can directly inhibit a type of human immuno-deficiency virus (HIV) found in late-stage AIDS.
Recent studies have even shown it to be an effective atypical anti-psychotic in treating schizophrenia, a disease many other studies have inconsistently found it causing.

Top 10 Health Benefits of Marijuana
1. Cancer
Cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals and also kill cancer cells. Western governments have known this for a long time yet they continued to suppress the information so that cannabis prohibition and the profits generated by the drug industry proliferated.
THC that targets cannabinoid receptors CB1 and CB2 is similar in function to endocannabinoids, which are cannabinoids that are naturally produced in the body and activate these receptors. The researchers suggest that THC or other designer agents that activate these receptors might be used in a targeted fashion to treat lung cancer.
2. Tourette’s Syndrome
Tourette’s syndrome is a neurological condition characterized by uncontrollable facial grimaces, tics, and involuntary grunts, snorts and shouts.
Dr. Kirsten Mueller-Vahl of the Hanover Medical College in Germany led a team that investigated the effects of chemicals called cannabinols in 12 adult Tourette’s patients. A single dose of the cannabinol produced a significant reduction in symptoms for several hours compared to placebo, the researchers reported.
3. Seizures

Marijuana is a muscle relaxant and has “antispasmodic” qualities that have proven to be a very effective treatment for seizures. There are actually countless cases of people suffering from seizures that have only been able to function better through the use of marijuana.
4. Migraines

Since medicinal marijuana was legalized in California, doctors have reported that they have been able to treat more than 300,000 cases of migraines that conventional medicine couldn’t through marijuana.
5. Glaucoma

Marijuana’s treatment of glaucoma has been one of the best documented. There isn’t a single valid study that exists that disproves marijuana’s very powerful and popular effects on glaucoma patients.
6. Multiple Sclerosis

Marijuana’s effects on multiple sclerosis patients became better documented when former talk-show host, Montel Williams began to use pot to treat his MS. Marijuana works to stop the neurological effects and muscle spasms that come from the fatal disease.
7. ADD and ADHD

A well documented USC study done about a year ago showed that marijuana is not only a perfect alternative for Ritalin but treats the disorder without any of the negative side effects of the pharmaceutical.
8. IBS and Crohn’s

Marijuana has shown that it can help with symptoms of the chronic diseases as it stops nausea, abdominal pain, and diarrhea.
9. Alzheimer’s

Despite what you may have heard about marijuana’s effects on the brain, the Scripps Institute, in 2006, proved that the THC found in marijuana works to prevent Alzheimer’s by blocking the deposits in the brain that cause the disease.
10. Premenstrual Syndrome

Just like marijuana is used to treat IBS, it can be used to treat the cramps and discomfort that causes PMS symptoms. Using marijuana for PMS actually goes all the way back to Queen Victoria.
Mounting Evidence Suggests Raw Cannabis is Best
Cannabinoids can prevent cancer, reduce heart attacks by 66% and insulin dependent diabetes by 58%. Cannabis clinician Dr. William Courtney recommends drinking 4 – 8 ounces of raw flower and leaf juice from any Hemp plant, 5 mg of Cannabidiol (CBD) per kg of body weight, a salad of Hemp seed sprouts and 50 mg of THC taken in 5 daily doses.
Why raw? Heat destroys certain enzymes and nutrients in plants. Incorporating raw cannabis allows for a greater availability of those elements. Those who require large amounts of cannabinoids without the psychoactive effects need to look no further than raw cannabis. In this capacity, it can be used at 60 times more tolerance than if it were heated.
Raw cannabis is considered by many experts as a dietary essential. As a powerful anti-inflammatory and antioxidant, raw cannabis may be right u there with garlic and tumeric.

Marco Torres, Prevent Disease
Waking Times

Those Pungent Smells Oozing Out of Marijuana Buds Are Actually Giving You Clues About What Their Effects Will Be Like

May 25, 2014 by  
Filed under 420 news, General News

source:alternet

Scientists are now formally acknowledging something that Cannabis consumers have long taken for granted: aroma is associated with effect.

Plant cannabinoids —21-carbon molecules found only in Cannabis— are odorless. It’s the terpenoids —components of the plant’s “essential oils”— that create the fragrance. Terpenoids contain repeating units of a 5-carbon molecule called isoprene and are prevalent in smelly herbs such as mints and sage, citrus peel, some flowers, aromatic barks and woods.

The aroma of a given plant depends on which terpenoids predominate. They tend to be volatile molecules that readily evaporate, and they’re very potent —all it takes is a few reaching the nose to announce their presence.

Evidence that “phytocannabinoid-terpenoid interactions” enhance the therapeutic effects of cannabis was presented by Ethan Russo, MD, at a conference in Israel in 2010 and published in the August 2011 British Journal of Pharmacology. Russo, a neurologist and ethnobotanist, is senior medical adviser at GW Pharmaceuticals.

Both terpenoids and cannabinoids are secreted inside the Cannabis plant’s glandular trichomes, and they have a parent compound in common (geranyl pyrophosphate). More than 200 terpenoids have been identified in Cannabis. The most common and most studied include limonene, myrcene, alpha-pinene, linalool, beta-caryophyllene, caryophyllene oxide, nerolidol and phytol. Anecdotal evidence suggests that pinene is alerting, limonene “sunshine-y,” and myrcene sedating.

The fact that most terpenoid compounds are common components of the human diet and “generally recognized as safe” by the Food and Drug Administration has made research possible, and scientists employed by flavor and fragrances manufacturers have investigated their properties over the years. But the terpenoids “remain understudied” in terms of therapeutic potential, according to Russo.

His paper mustered all the evidence —proof in some cases, hints in others—  that cannabinoids and terpenoids can work in concert to abate symptoms of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, fungal and bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA, which kills more Americans nowadays than AIDS) and other illnesses.

Jeffrey Hergenrather, MD, president of the Society of Cannabis Clinicians, who heard Russo’s presentation in Israel, expects its publication to “generate great interest in terpenes among medical cannabis users as well as physicians.” The SCC recently began collecting data on patients’ responses to CBD-rich Cannabis. Future surveys will seek to document which other cannabinoids and which terpenoids are associated with which effects.

The “Entourage Effect”

The conference at which Russo presented his paper was held at Hebrew University, Jerusalem, where Raphael Mechoulam directs a lab, in honor of Mechoulam’s 80th birthday.

In 1999 Mechoulam co-authored a paper with Shimon Ben-Shabat suggesting that cannabinoids made in the body work by means of an “entourage effect.” They had found that the endocannabinoid 2-AG (2-arachidonoylglycerol), when administered with two related compounds, would bind more readily at the cannabinoid receptors and exert more pronounced behavioral effect on mice.

To pharmacologists who customarily designed experiments aimed at finding the active ingredient, this had heavy implications. Mechoulam spelled them out: “Biochemically active natural products, from either plant or animal origin, are in many instances accompanied by chemically related though biologically inactive constituents. Very seldom is the biological activity of the active constituent assayed together with inactive ‘entourage’ compounds. Investigations of the effect of the active component in the presence of its ‘entourage’ compounds may lead to results that differ from those observed with the active component only.”

In 2001 John McPartland and Russo published a paper in the Journal of Cannabis Therapeutics applying the “entourage” concept to the plant itself.  “Good evidence shows that secondary compounds in cannabis may enhance the beneficial effects of THC… and reduce THC-induced anxiety, cholinergic deficits, and immunosuppresion,” they wrote. “Cannabis terpenoids and flavonoids may also increase cerebral blood flow, enhance cortical activity, kill respiratory pathogens, and provide anti-inflammatory activity.”

full story:

HEMP SEED: THE MOST NUTRITIONALLY

March 26, 2014 by  
Filed under 420 news

source:

by Lynn Osburn


Seeds of the plant cannabis sativa, hemp seed, contain all the essential amino acids and essential fatty acids necessary to maintain healthy human life.  No other single plant source has the essential amino acids in such an easily digestible form, nor has the essential fatty acids in as perfect a ratio to meet human nutritional needs.

The importance of hemp seed nutrients to human health cannot be  fully appreciated without some understanding of bio-chemistry in  life.  Unfortunately, any attempt to understand the flow of life  leads into the realm of the most troublesome of the three  infinities — the infinitely complex.

Some deep thinkers believe life is a paradox not to be understood  but experienced to the fullest.  However, the Sages have said,  “Know thyself.”  At any rate it is paradoxic to attempt simplifying  the infinite complexity of flowing life.  Yet, it is far better  for the health and development of any thinking and feeling,  uniquely individual human being, to pursue knowledge than to  lounge in ignorance.

One out of two Americans win die from the effects of  cardiovascular disease (CVD).  One out of four Americans will die from cancer.  Researchers believe cancers erupt when immune system response is weakened.  Pioneers in the fields of biochemistry and human nutrition now believe CVD and most cancers are really diseases of fatty degeneration caused by the continued over-consumption of saturated fats and refined vegetable oils that turn essential fatty acids into  carcinogenic killers.  And if this is not scary enough, more Americans are succumbing to immune deficiency diseases than ever before.  Sadly it is ignorance of human nutritional needs that will cause this overwhelming majority of Americans to die slowly from these afflictions — the greatest killers in affluent nations.


HEMP SEED PROTEINS AND THE BUILDING BLOCKS OF LIFE AND IMMUNITY
          There are eight amino acids the human body cannot make and two  more the body cannot make in sufficient quantity, so they are  essential to life.  A diet without any one of them will  eventually cause disease and death.  These essential amino acids, along with eleven others the body can make from them, are chained together in accordance to genetic guidelines, via RNA formats from DNA blueprints, into structural proteins that  give body to life, and into enzymes (globular proteins) that carry out the mechanics of living.

Nearly three quarters of body solids are proteins.  The body  is literally constructed and maintained by an infinitely complex system that simply builds proteins from amino acid sub units.  Every amino acid consists of an amine and a  carboxyl bound to the same carbon atom.  All but the smallest amino acid have one, more or less complex, carbon containing side chain connected to the carbon atom shared by the amine and carboxyl groups.  The amine group, ND, is slightly  basic;  the carboxyl group, COOH, is a mild acid.  The amine  group of one amino acid unites with the carboxyl group of  another forming a peptide link.  Proteins are made of amino  acid peptide chains in specific sequences.  The number of  possible amino acid peptide combinations is infinite.

Peptide chains can bend, twist and unite with other peptide chains by forming weak hydrogen bonds between nitrogen and oxygen atoms along the chain.  Amino acids can also form bonds through side chain linkages.  All three types of amino acid bonding methods contribute to the infinite possibility of protein shapes and reactivity potentials.  Though each species builds proteins unique to itself, life can tailor new ones if  challenged by the pressures of existence.

Hemp is not unique in having all the essential amino acids in its embryonic seed.  Flax seeds also contain all the  essential amino acids as do many other seeds in the plant  kingdom.  What is unique about hemp seed protein is that  65% of it is globulin edistin.  That is the highest in the  plant kingdom.

Globulins are one of seven classes of simple proteins.  Simple  proteins are constructed from amino acids and contain no  non-protein substances.  Globulins are in seeds and animal blood.  Edistins are found in seeds;  serum globulin is in  blood.  Edistins are plant globulins.  And globulins along with  albumins are classified as globular proteins.  All enzymes,  antibodies, many hormones, hemoglobin and fibrogin (the body  converts fibrogin into non-soluble, fibrin, a blood clotting  agent) are globular proteins.  They carry out the main work  of living.

Albumin, globulin and fibrogin are the three major types of  plasma proteins.  Plasma is the fluid portion of blood that supplies nutrients to tissues.  And the three protein  types:  serum albumin, serum globulin and fibrogin, compose  about 80% of plasma solids.  These plasma proteins serve as a  reservoir of rapidly available amino acids should any body  tissues be in need.

Plant seeds contain albumin and globulin but no  fibrogin.  Albumin is the nutritive material that fills the  space in the seed between the embryo and the seed coat.  The  embryo needs albumin to fuel its initial growth until  photosynthesis begins.  Globulin edistins within the embryo  guarantee this new life has the enzymes necessary for metabolic  activity.

Globulin is the third most abundant protein in the human body.  Globulins perform many enzymatic (causing reactions to take place) functions within the plasma itself.  More importantly,  they are responsible for both the natural and acquired immunity a  person has against invading organisms.  The body uses globulin  proteins to make antibodies which attack infecting agents  (antigens) that invade the body.  Globulins like gamma globulin  are absolutely essential to maintain a healthy immune system.  They neutralize alien microorganisms and toxins.

Globulins are divided into three classes:  alpha, beta and gamma globulins.  Alpha and beta globulins operate as transport  vehicles by combining with other substances and carry protein  from one part of the body to another.  They haul the materials  needed to build new and replace worn or damaged bodily  structures.  Gamma globulins are divided into five classes of  antibodies called immunoglobulins.  All are formed to combat  specific cell invading antigens.  They comprise the body’s  first line of defense against disease and  infection.  Immunoglobulins are produced by B lymphocyte (white  blood cells) plasma cell clones located in lymph system  nodes.  Infecting antigens normally must pass through the  lymph system before entering the blood stream.

Regarding human protein requirement:  “Qualitively, it is considered desirable to secure amino acids similar to those  of human tissues, both as to kinds and relative quantities  of the various kinds.”  [Textbook of Anatomy and Physiology, Kimber, Gray, Stackpole, 1943]

During digestion proteins in food are broken down into amino  acids.  The amino acids are then taken into the body and  reassembled into human proteins according to need and the availability of the amino acids necessary to make specific proteins.

The body needs the necessary kinds of amino acids in sufficient quantity in order to make proteins such as the globulins.  Proper quantities of the right kinds may not be available to the body much of the time.  So even though the body has enough essential amino acids available to prevent deficiency diseases, it may not have enough to build quantities of immunoglobulins necessary for the immune system to repel infection.

The best way to insure the body has enough amino acid material  to make the globulins is to eat foods high in globulin  proteins.  Since hemp seed protein is 65% globulin edistin, and also includes quantities of albumin, its protein is readily available in a form quite similar to that found in blood  plasma.  Eating hemp seeds gives the body all the essential  amino acids required to maintain health, and provides the  necessary kinds and amounts of amino acids the body needs to  make human serum albumin and serum globulins like the immune enhancing gamma globulins.  Eating hemp seeds could aid, if not heal, people suffering from immune deficiency  diseases.  This conclusion is supported by the fact that hemp  seed was used to treat nutritional deficiencies brought on by  tuberculosis, a severe nutrition blocking disease that causes  the body to waste away. [Czechoslovakia Tubercular Nutritional  Study, 1955]



ANTIBODIES

          Antibodies are globulin proteins programmed to destroy antigens (any substance eliciting a response from lymphocytes:  bacteria, viruses, toxins, living and dead tissue, internal debris, etc.).  Circulating in blood plasma like mines floating in a harbor antibodies await contact with the enemy, then initiate a cascade of corrosive enzymes that bore holes in the antigen surface causing it to break apart.

Antibodies are custom designed to neutralize or disintegrate  one specific type of antigen.  White blood cells called B  cell lymphocytes seek out and lock-on to antigenic proteins  or sugars on the invader’s surface.  The B cell then uses  that lock and key pattern to make antibodies tailored to  that antigen only.  It also will make clones of itself called plasma cells.  Most of the clones begin producing antibodies for that antigen.  Others become memory cells which may spend years wandering through the blood stream looking for that specific antigen.  If the body is exposed  to it again the memory cells lock-on to one and begin producing plasma cell clones and a flood of antibodies that wipe out the invader.  One lymphocyte can divide into hundreds of plasma cells in a few days.  A mature plasma cell can make about 2000 antibodies every second for the few days it lives.  This is how the body acquires immunity.

The body’s ability to resist and recover from illness depends upon how rapidly it can produce massive amounts of antibodies to fend off the initial attack.  If the  globulin protein starting material is in short supply the  army of antibodies may be too small to prevent the  symptoms of sickness from setting in.

Hemp seed is the premier plant-seed provider of globulin starting material — the highest in the plant kingdom.  Eating hemp seeds will insure the immune system has the reservoir of immunoglobulin resources needed to make disease destroying antibodies.

Globulin Antibody



Next issue: Part II, Hempseed        Oils and the Flow of Life Force

References:

  • Blood:  The River of Life, Jake Page;  Dr. Robert     A. Good, Dr. Lawrence S. Lessin, Dr. Kenneth C. Robbins,     consultants.  U.S. News Books 1981.
  • Fats and Oils: The Complete Guide to Fats and Oils in Health    and Nutrition, Udo Erasmus. Alive Books 1986.
  • Life and Energy:  An Exploration of the Physical and Chemical    Basis of Modern Biology, Isaac Asimov. Avon Books 1962.
  • Organic Chemistry, R. T. Morrison.  1960
  • Textbook of Anatomy and Physiology, Kimber, Gray, Stackpole.  1943
  • Textbook of Medical Physiology, Arthur C. Guyton,     MD. W. B. Sunders Company 1971.
  • Textbook of Organic Chemistry, E. Wertheim.  The Blakiston     Company 1945.

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